Multiple-Effect Distillation (WFI)

MS-01

Multiple-Effect Distillation (WFI) is designed to comply with the specifications of U.S. Pharmacopeia (USP) Water For Injection (WFI), and in accordance with the water quality of the supplied water source. When the temperature exceeds 80°C, the purification of water quality will be transferred in two phases.

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Changing to vapor from liquid, then changing to liquid from vapor. The feed water evaporates through the heat exchanger in the evaporator, and uses its latent heat to let the evaporation process through a series of 180 degree rotations by a centrifugal cyclone baffle plate device inside the separator. Forcing the particles and water drops out by the power of flow to make the vapor that leaving the baffle plate will not contain dissolved solids and pyrogens. The particles and water drops will fall to the bottom and be heated again, condensing the purified water vapor to required distilled water by condensation transferring, using a three-way valve to discharge the unqualified purity water to ensure the water quality of distilled water, and storing in a storage tank for injection pharmaceutical use.

Features

Water quality monitoring system.
The product is more energy-saving than traditional single-effect type.
Using double-tube plates design to prevent cross-contamination.
Using double-tube plates for cooling system to prevent cross-contamination.
Using double-tube plates for the first effect of evaporator to prevent cross-contamination.
Each evaporator has a window to observe the internal situation of the evaporator.
The heat-transfer tube’s expansion technology construction has good heat transfer efficiency and can be repaired and maintained.
The internal design of the heat-transfer tube is using the temperature differences to make internal circulation, which improving the efficiency of temperature rising.
The heat-transfer tube design of the heat exchanger improves the efficiency and achieves the energy-saving effect.
Using the latest design for the steam-water separated baffle of evaporator to reduce endotoxins in the water effectively.

Applications

For the Pharmaceutical.

Specification

Model	Number of Effects	5 Bar Steam Heating			Dimensions
Model	Number of Effects	Production Capacity (Lt/hr)	Steam (kg/hr)	Cooling Water (Lt/hr)	Height (mm)	Length (mm)	Width (mm)	Weight (mm)
MS-250/4	4	250	85	280	2500	1300	700	800
MS-500/4	4	510	150	500	2500	1300	900	900
MS-500/5	5	510	130	300	2500	1450	900	1000
MS-1000/5	5	1200	320	600	2900	1900	1000	2000
MS-1000/6	6	1200	270	600	2900	2240	1000	2300
MS-1500/5	5	1700	420	750	3200	3040	1050	2700
MS-1500/6	6	1700	350	750	3200	3350	1050	3000
MS-2000/5	5	2200	620	1000	3200	3000	1100	3300
MS-2000/6	6	2200	550	1000	3200	3430	1100	3800
MS-3000/6	6	3200	700	1200	3700	3900	1300	4800
MS-4000/6	6	4300	1000	1400	3900	4480	1400	6800

※ We can accept customer specify specification.

Construction & Structure

The equipment materials that connected to the water inlet are all using stainless steel SS316L, frosted and polished 320 ~ 400#.
Double-tube plate design, using distillation method to treat the contaminated cooling water through the glass fiber.
The external materials and flanges of the equipment are all using SS304.
The pipes are passivated before actual operation.
Double tube plate design. By using distillation method to treat contaminated cooling water through glass fiber.
The external materials and flanges of the equipment are using SS304.
The pipes are passivated before starting actual production.

Processing Map

Process

The equipment is using the working principle of heat exchanger, the first cylinder is heated by external steam, other cylinders are heated by the first cylinder's pure steam to next cylinder. Using evaporator and condenser to force the water to proceed twice variations. Details are described as follows:

First of all, letting the feed water that inside evaporator to pass through heat exchanger, the liquid will be changed to gaseous, then using its latent heat to get into separator. There's a special mist damper and a high centrifugal force cyclone device inside the separator, the steam will pass through 180 degree continuous rotation and separate particles, drops and pyrogen when passing through the special device that mentioned above. The steam that leaves separator is sterile and does not contain solution solid and pyrogen. The particles and drops will return to the bottom of evaporator cylinder and be heated again, only the high-speed purified steam can pass through the separator and get into condenser at this stage.

After that, proceeding the second variation, the steam that inside condenser will be changed to liquid (distillate) from steam by passing through cooling exchanger, and using diverter valve to ensure the quality of distilled water. If the water quality is lower than the purity setting, then it will be discharged to drainage pipe, otherwise, it will be flown to storage tank to provide for the purpose of pharmaceutical Water For Injection (WFI).

In addition, due to the fact that it adopts multiple effect type, it will be preheated by the first condenser before injecting water to each cylinder, meanwhile, the evaporation that inside feed water latent heat piping device for each cylinder is equipped with recovery device to save the consumption of steam energy.

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